Table of Contents
- 1 Mk 677 Ibutamoren Complete Review
- 1.1 What is MK 677 Ibutamoren?
- 1.2 How Does It Work?
- 1.3 Take a Look at the Scientific Backing
- 1.4 What are the Health Benefits?
- 1.4.1 Helps Build Muscles
- 1.4.2 Increased Endurance
- 1.4.3 Increases Bone Density
- 1.4.4 Reduces Muscle Wasting
- 1.4.5 Combats Aging and Increases Longevity
- 1.4.6 Improves Sleep
- 1.4.7 Treatment for Growth Hormone Deficiency
- 1.4.8 Considered a Nootropic
- 1.4.9 Helps Wound Healing and Tissue Regeneration
- 1.4.10 Prevents Tumor Growth
- 1.4.11 Possible Hangover Cure
- 1.5 What are the Side Effects?
- 1.6 What Dosage Should I Take?
- 1.7 Why is it Recommended for Bodybuilders?
- 1.8 Get the Results You Finally Want
- 1.9 Where Can I Buy Ibutamoren?
Mk 677 Ibutamoren Complete Review
Mk 677 Ibutamoren has been known to deliver some amazing results. We all know that some products are better than others when it comes to achieving your goals.
One product that has been a hot topic in forums, clinical research, and other highly-debated discussions is MK 677 Ibutamoren. Some people are calling this product a wonder drug that is not only ideal for bodybuilding and other strength training activities, but also as a possible cure for Alzheimer’s disease. It has even been called the “Fountain of Youth”.
Before trying out any health supplement, you should know exactly what it is, if there are any side effects, its health benefits, and any other related information.
Everything you need to know about Ibutamoren is provided here so that you can truly know for yourself if this is the right health product for you.
What is MK 677 Ibutamoren?
MK 677 Ibutamoren (Ibutamoren Mesylate) is a powerful supplement that you can use to improve your health to include metabolism, strength, longevity, bone density, and cognitive ability. It is also undergoing continuous research to investigate any benefits it may provide for the elderly, Alzheimer’s disease, and growth hormone deficiency.
This medication is sold over the counter and it can be taken orally. It is also very potent and long-lasting. Many companies market it as a selective androgen receptor modulator (SARM) which is increasing in popularity among bodybuilding products.
The reason SARMs are so popular is that they work the same way steroids do except that SARMs are selective and specifically target only androgen receptors. In other words, taking it is like taking a mild steroid but there are no immediate side effects.
On the other hand, Ibutamoren works differently because it does not function in the same way. A SARM targets an androgen receptor in the human body but Mk 677 does not. Therefore, it cannot be classified as a SARM.
Although SARMs can be quite harmless and possibly replace steroids altogether, there are some negative side effects related to SARMs that have not been studied and tested and they are still unknown. This factor makes it in a class of its own.
In scientific terms, it is a selective agonist of the ghrelin receptor which is a part of the brain that prepares the body to nourish, repair, grow, and be active. It also causes GH levels to increase tremendously. This is one of the reasons why it is called the fountain of youth because an increase in growth hormones makes you leaner, stronger, healthier, and improves hair and skin. Some studies have also shown that increased growth hormone levels make you smarter.
Mimics the growth hormone (GH)
Mk 677 Ibutamoren has been proven through studies to mimic the growth hormone (GH)-stimulating action of the peptide hormone ghrelin. This hormone is produced in the gastrointestinal tract when the stomach is empty. This is why ghrelin is often called the “hunger hormone”. When the stomach is stretched, this hormone is no longer produced. When an increased level of the hormone is present, it acts on the hypothalamic brain cells in the central nervous system to perform two functions. It works on the brain cells to increase hunger and it also increases gastric acid secretion and the gastrointestinal motility so that the body is prepared for food intake.
This powerful drug is also under development to potentially treat children and elderly adults who suffer from reduced levels of growth hormones and those with growth hormone deficiency. It is also a promising therapy for the treatment of frailty in the elderly since human studies have shown that it can increase both bone mineral density and muscle mass.
How Does It Work?
This product works by stimulating the growth of IGF-1. It also promotes the growth of essential hormone and IGFBP-3 secretion. It works as a pulse booster that stimulates the production of growth hormone. This can be used to raise the levels of the body’s production of essential hormone in the following ways:
– Encourages glands to release an increased level of Growth Hormone Releasing Hormone (GHRH)
– Works to decrease levels of somatostatin which is counteractive because somatostatin stops or slows down the release of growth hormone
– Increases levels of GHRH to be released exponentially by the pituitary gland
– Works by preventing or stopping the signaling of the somatostatin receptor
If all of that sounds very complicated, here is a simpler explanation. Growth hormones play an essential role in fighting a real-world fountain of youth. They are naturally at their highest levels during life periods when cognitive development is at its peak. This is why they are also considered as a cognitive enhancer for helping adults. During physical development, growth hormones are necessary and provide the signal for muscles to grow and proliferate which in turn creates more muscle cells to strengthen and mature.
Take a Look at the Scientific Backing
Several studies, clinical trials, and reports have been conducted on it. In 1995, one study was done where MK-677 was intravenously injected using different doses that range from 0.01 to 0.1 mg/kg. The results of this study showed that low doses of the drug had no impact but an increase in dosage indicated a clear body response. This study concluded that increases in growth hormone levels, starting with the first proper dose of Mk 677 Ibutamoren, will result in stimulation of natural growth hormone production.
The following year, another study that was published in the Journal of Clinical Endocrinology and Metabolism was conducted on healthy elderly adults who were given 25 mg of Mk 677 Ibutamoren per day. The main finding of this study showed that GH levels rose by 24% without exercise. For those who performed exercise, GH levels increased even further. In addition, this study provided enough evidence to conclude that boosting GH and IGF-1 levels proves to be beneficial in young adults and that it can also be used to boost GH levels in the elderly. In addition to fat burning properties due to an increase in blood sugar levels, results also showed that there was no increase in cortisol.
The results from this study were extremely helpful because unlike other products on the market that stimulate an increase in cortisol, MK-677 Ibutamoren does not. This is an important factor because cortisol is not a hormone that should be elevated. When there is an increase in cortisol levels, it suppresses the immune system, impairs learning and memory, and reduces wound healing.
In a follow-up study that was also published by the Journal of Clinical Endocrinology and Metabolism, the effects of a seven-day treatment in normal, healthy young men were examined. The results showed that Mk 677 Ibutamoren increases the frequency of GH pulses at a low amplitude instead of increasing levels of individual pulses. This study was important to show that there is a limit on how far the body’s internal organs can be pushed. It proves that MK-677 can be effective without overexerting the body in a negative way where it would go past its normal limits.
In 2001, a clinical trial was conducted to study the effects of MK-677 on the GH and IGH-1 levels in children who were growth hormone-deficient. The results of this study were remarkable in showing that it works well at any age even when there are deficiencies present. The main reason why it works so well is that it uses an alternative pathway to release growth hormones but intracellular signaling processes.
Continued studies examined the effectiveness of MK-677 over a 24-hour period. When healthy adults were given oral treatments of MK-677, measurements were taken to show that the drug remained in the body system at levels of 50% or more even after a few hours had passed. GH levels would be measured in the morning when doses were administered and then measurements would be taken later in the day. Results showed that GH levels nearly doubled several hours after the drug was administered.
Another study was conducted on the effect of Ibutamoren on catabolic states. Subjects consisting of healthy young men were subjected to short-term diet-induced nitrogen wasting while given a once-daily oral dose of 25 mg of MK-677 for seven days. The results showed a sustained increase GH and IGF-1 in concentrated levels. It also showed great potential for treatment of conditions involving muscle wasting because nitrogen wasting was reversed.
An additional study was done where subjects were given 25 mg of Ibutamoren daily for eight weeks to test the effects of the drug on fighting obesity. The results showed that lean body mass levels increased and neither visceral adipose tissue nor total body tissue was affected. The subjects in this clinical trial also showed higher serum levels of GH, IGF-1, and IGF-1 binding protein-3.
After two weeks, the results showed that there were also higher levels of the basal metabolic rate in subjects who were tested. This study was also concluded with a hypothesis that stated this supplement is responsible for helping achieve leaner body mass because the effect is caused by an appetite decrease and an increase in calorie deposition into the muscle. This hypothesis is in contrast to other opinions that MK-677 reduces fat stores directly.
There is a mountain of literature that proves its effectiveness. Other important points to note are that other studies have shown that this drug is not only effective, but it also does not affect prolactin levels and it actually lowers cortisol. When it was tested on functionally impaired elderly adults, the results showed that it also stimulates an increase in bone density. Some studies have also shown that it is a potential therapeutic target for treatment of the early stages of Alzheimer’s disease.
What are the Health Benefits?
The health benefits of are enormous and here are some of the many benefits it provides:
Helps Build Muscles
It is frequently used as an anabolic substance for bodybuilders who want to create bigger muscles while increasing lean body mass. When taken orally once a day, it is proven to be effective for many people who want to make a dramatic change in their physical appearance and provides a way to improve their body shape by building muscle.
As mentioned before, it increases growth hormone levels and IGF-1 which directly translates into reduced body fat and increased muscle mass and muscle strength. When combined with regular exercise, the results are fast and you will see a difference in the way you look in the mirror in as little as 7 days after using this product.
People who are searching for products that can help them improve their running times on the treadmill or get more results during their weightlifting sessions will find that Mk 677 Ibutamoren is exactly what they are looking for.
Increases Bone Density
As mentioned previously, GH increases bone turnover which results in an eventual increase in bone density. However, you will not see this increase immediately. When taking MK-677, it usually takes more than one year see an increase in bone density. In studies where subjects were treated with MK-677, subjects actually experienced an initial decrease in bone density before an eventual increase after one year.
In a study using healthy obese male volunteers, researchers discovered an increase in bone turnover. In elderly adults, osteocalcin, which is a marker of bone turnover was measured on subjects were given dosages which resulted in an increased bone building. Another study of it that consisted of volunteers comprised of postmenopausal women resulted in an increased in bone mineral density which helps to prevent osteoporosis and increase bone strength.
Reduces Muscle Wasting
A study using food-deprived healthy volunteers showed that it reverses diet-induced protein loss which is considered a cause of muscle wasting. Another study conducted on elderly patients with hip fractures showed that MK-677 provided a significant improvement in gait speed muscle strength and helps to reduce the number of falls.
Combats Aging and Increases Longevity
Multiple studies have shown that when it is taken daily, GH and IGF-1 levels will increase without any serious adverse effects. Since GH secretion and muscle mass both decline starting from puberty and continuing throughout an adult’s life, a study of the effects of MK-677 on the elderly showed that the drug increases both GH and IGF-1 levels to those of healthy young adults. Another study also found that it rejuvenates the growth hormone profile in people who are obese. As a result, it is proven to have both anti-aging properties and beneficial effects on longevity. In addition, scientists from many different countries around the world agree that higher levels of GH are very beneficial and help to reverse the aging process.
Studies that were conducted on both young and elderly subjects have shown that people who take it daily experience an improved quality of sleep and better rapid eye movement (REM) sleep duration.
Treatment for Growth Hormone Deficiency
MK-677 was shown in a study to increase IGF-1 and IGFBP-3 growth hormone levels in children who suffered from growth hormone deficiency. The effects of taking the drug were achieved without changing the concentrations of other hormones needed for child development to include glucose, prolactin, thyroxine, triiodothyronine, thyrotropin, insulin, or cortisol. In addition, another study of severely GH-deficient men showed an increase in growth hormone and IGF-1 without changing the concentrations of glucose, prolactin, thyroxine, triiodothyronine, thyrotropin, insulin, or cortisol.
Considered a Nootropic
Since MK-677 works to activate the ghrelin receptor, many people consider it as a nootropic because of its effects. However, there is still not enough scientific proof to show if and how it affects cognitive performance. The drug has been shown to use two indirect mechanisms which can improve brain function which are:
1. Increases sleep quality and REM sleep duration which is essential for good cognitive function.
2. Increases IGF-1 which is known to improve learning and memory ability.
Helps Wound Healing and Tissue Regeneration
With an increase in growth hormones, people who take MK-677 experience an increase in tissue regeneration and wound healing. Although scientific studies lack in this claim, several people online who discuss this topic and forms and other websites often support the claim.
Prevents Tumor Growth
According to research that was performed on older mice, MK-677 was found to have an effect on preventing the growth of tumors.
Possible Hangover Cure
Although there is no scientific proof to back up the claim, many people report being able to cure their hangovers after a long night of binge drinking with MK-677.
What are the Side Effects?
People who experience side effects while taking it report that they sometimes experience an elevated appetite, muscle pain, and edema in the lower extremity. Several studies also reported a decrease in insulin sensitivity and an increase in fasting blood glucose. When observing people with elevated growth hormone levels, similar side effects included insulin resistance and joint pain.
A majority of studies report little to no side effects when taking it, there was one study that was terminated because of the patients who were tested. There was a study conducted on elderly patients with hip fractures who took doses of MK-677 and experienced elevated blood pressures, increase blood glucose levels, and some cases of congestive heart failure which is why the study was terminated. The patients who experienced congestive heart failure were all over the age of 80 and had no prior history of heart failure.
Other studies have reported that elevated levels of GH can cause skin problems, numb hands, muscle weakness, weight gain, slightly increased appetite, and insulin sensitivity.
When taking MK-677, it is important to watch your carbohydrate intake and regularly check insulin and blood sugar levels. This supplement should be avoided since it is an anabolic and both IGF-1 and growth hormone have the potential to cause cancerous tissue to grow. GH also has properties which stimulate the immune system which is why this supplement may not be suitable for those who are Th1 dominant.
Genetics also affect the response to Ibutamoren. It may be a good idea for you to get help to interpret your genes and you can do this using a genetic application. Genetic applications are offered by various companies online where you sign up, pay a fee, and put your raw data to their system to see what versions of certain genes (alleles) you have. GHSR is the gene that corresponds to the ghrelin receptor. When MK-677 or ghrelin activates the receptor, a signal is sent to the pituitary gland to start releasing growth hormone. It is better to have the following genes increased:
What Dosage Should I Take?
The most commonly used commonly used dose per day that is recommended to provide the maximum benefit with the least side effects is 25 mg per day. However, you will find that the product is sold in either powder or liquid form ranging from 5 mg up to 1000 mg or more. With a solid powder form, you can divide your dosages up more carefully and break them down into the recommended 25 mg daily dosage. This will also help you save money versus other products that come in pill form, are more expensive, and do not provide the convenience of breaking down dosages so easily.
Taking your dose once a day is fine since the half-life of Mk 677 Ibutamoren is 24 hours. Many people recommend that you take your dose before going to bed because the initial growth hormone pulses have the potential to make some individuals feel tired. This is often a common effect of high-quality growth hormone which is why it is recommended that you take your dose before bedtime so that you will not feel lethargic when you wake up.
It is totally up to you how long you want to plan your cycle duration. Some individuals have reported online that they have taken the supplement for a year or more and show no signs of side effects. As a result, there is no reason to have a predetermined safe cycle length and you can run Mk 677 Ibutamoren for as long as you want without having to worry about natural GH output or desensitization of your pituitary gland. For those who are cautious, you can keep your cycle length to around 12 weeks but it can actually be used for long durations of time. Many people never come off because they love the product that much.
Why is it Recommended for Bodybuilders?
Bodybuilders are always looking for the next best product that can help them gain more muscle and improve their performance. There are thousands of products out there that all claim to provide some type of benefit. However, the potential side effects of many of these products are what most people want to avoid. Common side effects and other health-related problems with these products often include:
– Increased weight gain
– Pattern baldness
– High blood pressure
– Many others
This is where Mk 677 Ibutamoren comes into play because it has been scientifically studied and lab tested over and over again. After so many studies and tests, the results have shown that Mk 677 is proven to be one of the most ideal supplements out there for bodybuilding; as well as any other activity that involves strength training.
Mk 677 Ibutamoren is also best for bodybuilding because it will not affect your testosterone levels in any capacity at all in a negative way. After taking this supplement, there is no need to complete a PCT phase or take an aromatase inhibitor which is required for other products.
Furthermore, when you take an oral dose, you will immediately increase the release of growth hormone and IGF-1 which is released from the pituitary gland through strong GH pulsations for the next 24 hours. These strong pulses cause your body to create growth hormone releasing peptides that are released naturally instead of treatments many bodybuilders use to take using multiple injections of growth hormone-releasing peptides. With Mk 677 Ibutamoren, it is taken orally and all growth hormone pulsations over the next 24 hours are released from one single dose.
With this high level of oral bioavailability, it does not require any injections and only one dose is needed to reap all the benefits. Before, bodybuilders used to take HGH injections and GH peptide injections that would be required to take in doses that occurred several times a day. You can imagine how uncomfortable this is in addition to the inconvenience when you have to travel since HGH and peptides require refrigerated storage even while traveling.
After ingestion, it stimulates the pituitary gland to cause 12 intense GH pulsations. In order to achieve the same benefit from peptides, you would have to inject GHRP-6 at least 12 times or more per day to achieve the same benefit. In addition, this supplement is stored at room temperature which makes it easy for travel.
With each consecutive day of use, hormone secretion levels will continue to go up to increasingly higher levels. As this occurs, these higher levels will allow your body to determine how much muscle you will be capable of packing on. In addition, weight gain is rapid and very noticeable in a good way and body fat melts off easier than before. It is not uncommon for someone who is taking it to gain up to 10 pounds within their first week of using the supplement.
As an athlete, sleep quality is just as important as your workout routine to repair and recover. It has been proven to provide better sleep quality that is deeper and dramatically improved due to an increased growth hormone output. Not only will you feel much stronger during workout routines, but you will also see significant increases in nitrogen retention. As a result, you will see muscular development like never before and your endurance will also be greatly enhanced. There will also be an improvement in your complexion to include healthier skin and hair.
Get the Results You Finally Want
Here is a summary highlighting what Mk 677 Ibutamoren can do for you so that you finally get the results you have always wanted:
– Boosts GH levels by releasing GHRH
– Reduces somatostatin release which turns off the release of the hormone
– One single dose is effective and the longer it is used, the better the results
– The longer the compound is used, the more GH levels increase
– Has been used in studies that were conducted for up to 2 years
– Activates brain regions to include opioid, dopamine, pituitary, and the hypothalamus which play a role in metabolic action
– Increases muscle mass by signaling cells to grow and creating more muscle cells
– Stimulates cells to begin growing
– Lowers fat mass
– Performs in the same way as insulin
– Utilizes fat stores as an energy source
– Delivers glucose to cells so it can be used
– Firmer, healthier skin and improved complexion
Where Can I Buy Ibutamoren?
There are lots of places where you can buy Mk 677 Ibutamoren supplements and there are tons of companies online selling different varieties of this product in supplement form. It is important that you take your time and do plenty of research before you go out and buy any Mk 677 Ibutamoren product since all of them are not the same. Make sure to educate yourself on the dosages of the growth hormone, mechanism, and its benefits. There is a reason why Mk 677 Ibutamoren is becoming one of the hottest supplements on the market today and one of the main ones is that bodybuilders and athletes are getting some really amazing results.
One recommended place to get MK677 Ibutamoren is Proven Peptides. This research chemical store offers the highest chemical purity of Mk 677 Ibutamoren possible. One thing that sets them apart is that all of the products they sell have been thoroughly tested and scientifically researched. All of this is combined with excellent customer service, fast reliable shipping, and high-quality packaging. To get started with Mk 677 Ibutamoren so you can reap all of the amazing benefits that it has to offer, click here to visit Proven Peptides so you can get started today.